CD105 Antibody from BIORBYT LTD.

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Antigenic SpecificityCD105
CloneMEM-229
Host SpeciesMouse
Reactive Specieshuman, porcine
IsotypeIgG2a
Formatallophycocyanin (APC) conjugate
Size100 tests
Concentrationn/a
ApplicationsFC
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DescriptionCD105 (endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
ImmunogenRecombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.
Other NamesEndoglin, END, ENG, HHT1, ORW1
Gene, Accession #UniProt: P17813, Gene ID: 2022
Catalog #orb1909791
Price$439
Order / More InfoCD105 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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St Louis, MO 63132
Email: info@biorbyt.com
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