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Antigenic Specificity | FBW7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to FBW7.F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination andsubsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds tophosphorylated target proteins. FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1released notch intracellular domain (NICD), and probably PSEN1. |
Immunogen | N-terminal region of human DDB1 |
Other Names | FBW7,Fbox,WD repeatcontaining protein 7,Archipelago homolog,hAgo,Fbox and WD40 domaincontainingprotein 7,Fbox protein FBX30,SEL10,hCdc4,FBW7,FBX30,SEL10 |
Gene, Accession # | UniProt: Q969H0 |
Catalog # | orb67185 |
Price | $527 |
Order / More Info | FBW7 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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