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Antigenic Specificity | Phospho-JAK2/3 (Tyr966/939) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. |
Immunogen | Synthesized Phospho peptide derived from human JAK2/3.at AA range: T966 |
Other Names | Tyrosine-protein kinase JAK2/JAK3 (EC 2.7.10.2; Janus kinase 2/Janus kinase 3; JAK-2/JAK-3) |
Gene, Accession # | Gene ID: 3717, UniProt: O60674 |
Catalog # | orb1730659 |
Price | $296 |
Order / More Info | Phospho-JAK2/3 (Tyr966/939) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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