KAISO pairs Antibody from BIORBYT LTD.

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Antigenic SpecificityKAISO pairs
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size100 ul
Concentration100 µg/ml BSA
ApplicationsWB
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DescriptionRabbit polyclonal to KAISO. KAISO antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody pairs-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody pairs arrays, Western blot, IP-Western, ChIP, IHC, and FACS. KAISO is also known as Zinc finger and BTB domain-containing protein 33, a transcriptional regulator with bimodal DNA-binding specificity. KAISO binds to methylated CpG dinucleotides in the consensus sequence 5-CGCG-3 and also binds to the non-methylated consensus sequence 5-CTGCNA-3. KAISO can recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. In contrast, KAISO may also activate transcription of a subset of target genes by the recruitment of CTNND2.
Immunogen2 distinct N-terminal regions of mouse KAISO
Other NamesZBTB33 pairs, ZNF348 pairs, Zinc finger and BTB domain-containing protein 33 pairs
Gene, Accession #UniProt: Q8BN78
Catalog #orb131766
Price$462
Order / More InfoKAISO pairs Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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