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Antigenic Specificity | Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human Erk1 |
Other Names | MAPK1/MAPK3 |
Gene, Accession # | Gene ID: 5595, 5594, UniProt: P28482 |
Catalog # | orb1732992 |
Price | $345 |
Order / More Info | Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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