GFAP Antibody from BIORBYT LTD.

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Antigenic SpecificityGFAP
CloneS206A-8
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatATTO-390 conjugate
Size100 ug
Concentration1 mg/ml
ApplicationsICC, IHC, WB
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DescriptionMouse monoclonal to GFAP (ATTO-390). The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia..
ImmunogenSynthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse
Other NamesGlial fibrillary acidic protein, Intermediate filament protein, Astrocyte, gfapl, DKFZp459C0729, MGC139638, FLJ45472, AI836096, GFAP
Gene, Accession #Gene ID: 2670, UniProt: P14136
Catalog #orb150515
Price$575
Order / More InfoGFAP Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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