IL22RA2 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-IL22RA2 antibody, protein, ELISA kits.
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| Antigenic Specificity | IL22RA2 |
| Clone | IL22RA2/7291 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2, kappa |
| Format | unconjugated |
| Size | 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-22RAlpha2 (Interleukin-22 receptor Alpha2 chain), also known as IL-22 binding protein (IL-22BP), cytokine receptor family class II member 10 (CRF2-10) or CRF2- soluble 1 (CRF2-S1), is a soluble, nonsignaling single chain receptor for IL-22. It is highly expressed in intestine and lymph nodes and is also found in spleen, kidney and liver. IL-22RAlpha2 has a cytokine-binding domain that contains two FnIII domains. Its affinity for IL-22 is 4- to 10-fold higher than that of the membrane-bound IL-22 receptor, however it has a dissociation rate up to 20 times lower. By binding to IL-22, IL-22RAlpha2 prevents the binding to the IL-22 membrane-bound receptor and therefore inhibits IL-22 signaling. This suggests that IL-22RAlpha2 may be important in regulating inflammatory responses. In addition, IL-22RAlpha2 can be induced by lipopolysaccharides (LPSs). |
| Immunogen | A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IL22RA2 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q969J5 |
| Catalog # | orb1823061 |
| Price | $405 |
| Order / More Info | IL22RA2 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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