PI3 Kinase p85 alpha Antibody from BIORBYT LTD.

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Antigenic SpecificityPI3 Kinase p85 alpha
Clone1C8
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsIHC, WB
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DescriptionBinds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
ImmunogenPurified recombinant protein expressed in E.coli.
Other NamesPIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Gene, Accession #Gene ID: 5295, UniProt: P27986
Catalog #orb1732580
Price$345
Order / More InfoPI3 Kinase p85 alpha Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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P: +44 (0)1223 859 353
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