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Antigenic Specificity | NKX2.2 |
Clone | NX2/1523 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. |
Immunogen | A human partial recombinant protein corresponding to amino acids 1-119 was used as the immunogen for this NKX2.2 antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 4821, UniProt: O95096 |
Catalog # | orb386099 |
Price | $764 |
Order / More Info | NKX2.2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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