PIAS1 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | PIAS1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | serum |
| Size | 100 ul |
| Concentration | n/a |
| Applications | IF, IHC, IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to PIAS1.E3 SUMO-protein ligase PIAS1 is a member of the mammalian PIAS (protein inhibitor of activatedSTAT-1 (signal transducer and activator of transcription-1)) family, which contains a putative zincbindingmotif and a highly acidic region. PIAS1 functions as an E3-type small ubiquitin-like modifier(SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMOtetheringfactor. PIAS1 plays a crucial role as a transcriptional coregulation in various cellularpathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway.In vitro, PIAS1 binds A/T-rich DNA. The effects of the transcriptional coregulation, transactivation orsilencing, may vary depending upon the biological context. |
| Immunogen | C-terminal region of human PIAS1 |
| Other Names | PIAS1,E3 SUMOprotein ligase PIAS1,DEAD,H boxbinding protein 1,Protein inhibitor of activated STATprotein 1,DDXBP1,GBP,RNA helicase IIbinding protein,GU,RHII,zinc finger,MIZtype containing3,ZMIZ3,Gubinding protein,AR interacting protein |
| Gene, Accession # | UniProt: O88907 |
| Catalog # | orb67014 |
| Price | $462 |
| Order / More Info | PIAS1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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