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Antigenic Specificity | NSE / Neuron Specific Enolase |
Clone | ENO/8253R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This monoclonal antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament. |
Immunogen | A recombinant fragment of human NSE gamma (within amino acids 234-434) was used as the immunogen for the NSE antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P09104 |
Catalog # | orb1825886 |
Price | $764 |
Order / More Info | NSE / Neuron Specific Enolase Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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