NSE / Neuron Specific Enolase Antibody from BIORBYT LTD.

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Antigenic SpecificityNSE / Neuron Specific Enolase
CloneENO/8253R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG, kappa
Formatunconjugated
Size100 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionThis monoclonal antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.
ImmunogenA recombinant fragment of human NSE gamma (within amino acids 234-434) was used as the immunogen for the NSE antibody.
Other Namesn/a
Gene, Accession #UniProt: P09104
Catalog #orb1825886
Price$764
Order / More InfoNSE / Neuron Specific Enolase Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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