MART-1 / Melan-A Cocktail Antibody from BIORBYT LTD.

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Antigenic SpecificityMART-1 / Melan-A Cocktail
CloneM2-7C10 + M2-9E3
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2b
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsFACS, IF, IHC-P, WB
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DescriptionThis antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This mAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
ImmunogenRecombinant human protein was used as the immunogens for this Melan-A antibody cocktail.
Other Namesn/a
Gene, Accession #UniProt: Q16655
Catalog #orb385744
Price$764
Order / More InfoMART-1 / Melan-A Cocktail Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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