FLI1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | FLI1 |
| Clone | FLVI1-1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG |
| Format | Protein G purified |
| Size | 20 ug, 100 ug |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Friend leukemia integration 1 is a member of the ETS family of DNA binding transcription factors that is involved in cellular proliferation and tumorigenesis. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewing's Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11;22)(q24;q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi's Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII. |
| Immunogen | Human partial recombinant protein (amino acids 107-216) was used as the immunogen for this FLI1 antibody. |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 2313 |
| Catalog # | orb750169 |
| Price | $405 |
| Order / More Info | FLI1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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