CD170 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | CD170 |
| Clone | 1A5 |
| Host Species | n/a |
| Reactive Species | human, primate |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | FC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD170, also known as Siglec 5 (sialic acid binding Ig-like lectin 5) is a type 1 transmembrane glycoprotein containing two cytoplasmic immunoreceptor tyrosine inhibitory motifs (ITIMs). CD170 forms homodimers and functions as an inhibitory receptor able to downregulate cell activation. It binds to alpha2,3- and alpha2,6-linked sialic acid ligands, e.g. on glycophorin A (CD235a). Aberrant expression of CD170 by CD34+ progenitor cells can be observed in case of acute myeloid leukemias. |
| Immunogen | Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1 |
| Other Names | OBBP2, OB-BP2, SIGLEC-5, SIGLEC5 |
| Gene, Accession # | Gene ID: 8778, UniProt: O15389 |
| Catalog # | orb1881228 |
| Price | $439 |
| Order / More Info | CD170 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240
info@biorbyt.com
http://www.biorbyt.com
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Email: info@biorbyt.com
Phone: +1 (415) 906-5211
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