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Antigenic Specificity | Phospho-Leptin Receptor (Tyr1141) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity). |
Immunogen | Synthetic peptide of human LEPR |
Other Names | Leptin receptor; LEP-R; HuB219 OB receptor; OB-R; CD295; LEPR; DB; OBR |
Gene, Accession # | Gene ID: 3953, UniProt: P48357 |
Catalog # | orb1730593 |
Price | $296 |
Order / More Info | Phospho-Leptin Receptor (Tyr1141) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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