Estrogen Receptor alpha Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Estrogen Receptor alpha antibody, protein, ELISA kits.
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| Antigenic Specificity | Estrogen Receptor alpha |
| Clone | NR3Ga-1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. It is found in two forms, alpha and beta. Both forms are widely expressed, however, alpha is the predominant form in endometrium and breast cancer cells, and beta is more highly expressed in brain, kidney, heart, lung and bone. Activated Estrogen receptor dimerizes and forms both homo- and heterodimers. ER contains five domains: A-F. The A and B domain are able to weakly activate ER in the absence of ligand. The C domain binds DNA and the E domain contains the ligand binding site. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This antibody is specific to estrogen receptor alpha and shows minimal cross-reaction with other members of the family. |
| Immunogen | Estrogen Receptor alpha protein (aa 2-185) was used as the immunogen for this antibody. |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 2099 |
| Catalog # | orb385818 |
| Price | $764 |
| Order / More Info | Estrogen Receptor alpha Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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