ITGA4 Antibody from BIORBYT LTD.

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Antigenic SpecificityITGA4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size100 ul
Concentrationn/a
ApplicationsWB
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DescriptionRabbit polyclonal to ITGA4.Integrin alpha-4 (ITGA4) is a single-pass type I membrane protein that belongs to the intergrin alphachain family. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. Theyrecognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin.They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S inVCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T inMADCAM1. On activated endothelial cells, integrin VLA-4 triggers homotypic aggregation for mostVLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with targetcells.
ImmunogenN-terminal region of human ITGA4
Other NamesITGA4,Integrin alpha4,CD49 antigenlike family member D,Integrin alphaIV,VLA4 subunit alpha,CD49d,CD49D
Gene, Accession #UniProt: P13612
Catalog #orb67043
Price$527
Order / More InfoITGA4 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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