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Antigenic Specificity | Versican |
Clone | S351-23 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | PerCP conjugate |
Size | 100 ug |
Concentration | 1 mg/ml |
Applications | ICC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to Versican (PerCP). Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a Lectinlike sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length and degree of modification by glycoaminoglycan chains. Accumulation around smooth muscle cells in lesions of athero-sclerosis suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may faciliatate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels.. |
Immunogen | Fusion protein amino acids 362-585 (glycosaminoglycan alpha domain) of mouse Versican core protein |
Other Names | Chondroitin sulfate proteoglycan 2, CSPG2, ERVR, GHAP, PG-M, VCAN, Chondroitin sulfate proteoglycan 2, Chondroitin sulfate proteoglycan core protein 2, Glial hyaluronate binding protein, Glial hyaluronate-binding protein, Large fibroblast proteoglycan, Large fibroblast proteoglycan, PGM, V1 Neo, Versican core protein, Versican proteoglycan, Versican V0, WGN 1, WGN, WGN1 |
Gene, Accession # | Gene ID: 13003, UniProt: Q62059 |
Catalog # | orb150494 |
Price | $572 |
Order / More Info | Versican Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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