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Antigenic Specificity | EHMT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to EHMT2.Euchromatic histone-lysine N-methyltransferase 2 (EHMT2) belongs to the histone-lysinemethyltransferase family, Suvar3-9 subfamily. EHMT2 specifically mono-and dimethylates 'Lys-9' ofhistone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tagfor epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT2also weakly methylates 'Lys-27' of histone H3 (H3K27me). In addition, EHMT2 is required for DNAmethylation, which is independent of its histone methyltransferase activity. Furthermore, EHMT2methylates non-histone proteins, including p53/TP53, CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6,KLF12 and itself. |
Immunogen | middle region of human EHMT2 |
Other Names | EHMT2,Histonelysine Nmethyltransferase EHMT2,Euchromatic histonelysine Nmethyltransferase 2,HLABassociated transcript 8,Histone H3K9 methyltransferase 3,H3K9HMTase 3,Lysine Nmethyltransferase1C,Protein G9a,BAT8,C6orf30,G9A,KMT1C,NG36 |
Gene, Accession # | UniProt: Q96KQ7 |
Catalog # | orb67069 |
Price | $527 |
Order / More Info | EHMT2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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