PAX8 Antibody from BIORBYT LTD.
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|---|---|
| Antigenic Specificity | PAX8 |
| Clone | rPAX8/1492 |
| Host Species | Recombinant Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors. |
| Immunogen | A recombinant human partial protein (amino acids 60-261) was used as the immunogen for this recombinant PAX8 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q06710 |
| Catalog # | orb640000 |
| Price | $764 |
| Order / More Info | PAX8 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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