BRAF Antibody from BIORBYT LTD.

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Antigenic SpecificityBRAF
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size200 ul, 100 ul, 50 ul
Concentrationn/a
ApplicationsIHC, WB
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DescriptionRabbit polyclonal antibody to BRAF. B-Raf, also know as c-Rmil, is a Serine/Threonine protein kinase member of the Raf family which includes Raf-1 and A-Raf. B-Raf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Composed of three conserved region (CR1, CR2, CR3) B-Raf is expressed primarily in the brain and in the nervous system. It has been observed that MAPK is activated by B-Raf in response to nerve growth factor. More than 60% of malignant melanomas were found to contain a specific mutation, B-Raf (V599E) the product of which possesses constitutive kinase activity. Mutations in B-Raf have also been identified in lung cancer and non-Hodgkin lymphoma.
ImmunogenRecombinant fusion protein of human B-Raf(NP_004324.2).
Other NamesB-RAF1, BRAF1, NS7, RAFB1, Proto-oncogeneB-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1
Gene, Accession #UniProt: P15056
Catalog #orb153753
Price$490
Order / More InfoBRAF Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

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Biorbyt LLC
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Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558


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