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Antigenic Specificity | CHEK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to CHEK1.Serine/threonine-protein kinase Chk1 (CHEK1) belongs to the CAMK Ser/Thr protein kinase family.CHEK1 is required for checkpoint mediated cell cycle arrest in response to DNA damage or thepresence of unreplicated DNA. CHEK1 also acts to integrate signals from A and ATR, two cellcycle proteins involved in DNA damage responses, that also associate with chromatin in meioticprophase I. Phosphorylation of CDC25A protein phosphatase by CHEK1 is required for cells to delaycell cycle progression in response to double-strand DNA breaks. |
Immunogen | C-terminal region of human CHEK1 |
Other Names | CHEK1,Serine,threonineprotein kinase Chk1,CHK1,CHK1 checkpoint homolog,Cell cycle checkpointkinase,Checkpoint kinase1 |
Gene, Accession # | UniProt: O14757 |
Catalog # | orb67288 |
Price | $527 |
Order / More Info | CHEK1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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