INSM1 / Insulinoma associated protein 1 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-INSM1 / Insulinoma associated protein 1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | INSM1 / Insulinoma associated protein 1 |
| Clone | INSM1/7992R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | unconjugated |
| Size | 100 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Insulinoma-associated protein 1 (INSM1) is a developmentally regulated zinc-finger transcription factor. It localizes to the nucleus and is expressed in embryonic issues undergoing neuroendocrine differentiation. INSM1 is not expressed in normal adult tissues but can be found highly expressed in neuroendocrine tumors. INSM1 is positive in 95% of lung small cell carcinoma and 91% of lung large cell neuroendocrine carcinoma, compared with 75% and 78% with the combined panel of traditional neuroendocrine markers (synaptophysin, chromogranin, and CD56).INSM1 stains 100% of the atypical carcinoids, typical carcinoids and paragangliomas, but only 3% of adenocarcinomas and 4% of squamous cell carcinomas. Therefore, INSM1 is sensitive and specific to be a single first-line pan-neuroendocrine marker. |
| Immunogen | A recombinant partial protein sequence (within amino acids 1-300) from the human protein was used as the immunogen for the IA1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q01101 |
| Catalog # | orb1824143 |
| Price | $764 |
| Order / More Info | INSM1 / Insulinoma associated protein 1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240
info@biorbyt.com
http://www.biorbyt.com
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558
Profile of BIORBYT LTD.
Return to Antibodies