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Antigenic Specificity | Phospho-HDAC5 (Ser498) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. |
Immunogen | Synthetic peptide of human HDAC5 |
Other Names | HD5; NY-CO-9 |
Gene, Accession # | Gene ID: 10014, UniProt: Q9UQL6 |
Catalog # | orb1730620 |
Price | $296 |
Order / More Info | Phospho-HDAC5 (Ser498) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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