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Antigenic Specificity | SATB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to SATB1.Special AT-rich sequence-binding protein 1 (SATB1) is a chromatin organizer and transcription factorthat integrates chromatin architecture with gene regulation. SATB1 binds to nuclear matrix/scaffoldassociatingAT-rich DNA sequences (MARs/SARs). It has been shown that SATB1 interacts withpromyelocytic leukemia protein (PML), and that SATB1 and PML function as a regulatory complexthat controls transcription by restructuring the dynamic chromatin-loop architecture. SATB1 isimplicated as a key regulator of the differentiation and activation of T cells. In cancer, SATB1 hasbeen shown to reprogram chromatin organization and the transcription profiles of breast tumors topromote growth and metastasis. |
Immunogen | C-terminal region of human SATB1 |
Other Names | SATB1,OTTHUMP00000207689,Special ATrich sequencebinding protein 1 |
Gene, Accession # | UniProt: Q01826 |
Catalog # | orb66710 |
Price | $527 |
Order / More Info | SATB1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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