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Antigenic Specificity | Lambda Light Chain Cocktail |
Clone | LcN-2 + ICO-106 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IF, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody cocktail is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Lambda light chain antibody is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. |
Immunogen | Purified human Ig (LcN-2 and ICO-106) was used as the immunogen for this Lambda Light Chain antibody cocktail. |
Other Names | n/a |
Gene, Accession # | Gene ID: 3535 |
Catalog # | orb248406 |
Price | $764 |
Order / More Info | Lambda Light Chain Cocktail Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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