Integrin beta 3 Antibody from BIORBYT LTD.

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Antigenic SpecificityIntegrin beta 3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size100 ul
Concentrationn/a
ApplicationsELISA, IHC, WB
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DescriptionIntegrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).
ImmunogenThe antiserum was produced against synthesized peptide derived from the C-terminal region of human ITGB3. AA range:621-670
Other NamesITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61
Gene, Accession #Gene ID: 3690, UniProt: P05106
Catalog #orb1730127
Price$296
Order / More InfoIntegrin beta 3 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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