Phospho-LRRK2 (Ser395) Antibody from BIORBYT LTD.

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Antigenic SpecificityPhospho-LRRK2 (Ser395)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatunconjugated
Size100 ul
Concentrationn/a
ApplicationsICC, WB
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DescriptionPositively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.
ImmunogenA synthesized peptide derived from human Phospho-LRRK2 (S935)
Other NamesAURA17; Dardarin,, Leucine rich repeat kinase 2; LRRK 2, LRRK2; LRRK2_HUMAN; PARK 8; PARK8; RIPK7; ROCO 2; ROCO2
Gene, Accession #Gene ID: 120892, UniProt: Q5S007
Catalog #orb1730696
Price$296
Order / More InfoPhospho-LRRK2 (Ser395) Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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