CKMT1 Antibody from BIORBYT LTD.

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Antigenic SpecificityCKMT1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG1
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsWB
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DescriptionCreatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
ImmunogenPurified recombinant human CKMT1 protein fragments expressed in E.coli.
Other NamesCKMT; CKMT1; UMTCK; CKMT1A
Gene, Accession #Gene ID: 1159, UniProt: P12532
Catalog #orb1732562
Price$345
Order / More InfoCKMT1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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F: +44(0)1223 280 240

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