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Antigenic Specificity | CKMT1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Creatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. |
Immunogen | Purified recombinant human CKMT1 protein fragments expressed in E.coli. |
Other Names | CKMT; CKMT1; UMTCK; CKMT1A |
Gene, Accession # | Gene ID: 1159, UniProt: P12532 |
Catalog # | orb1732562 |
Price | $345 |
Order / More Info | CKMT1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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