SC35 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-SC35 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SC35 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | IHC, IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway. The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment. |
| Immunogen | A synthetic peptide of human SC35 |
| Other Names | Protein PR264; Splicing component; 35 kDa; Splicing factor SC35; SC-35; Splicing factor; arginine/serine-rich 2 |
| Gene, Accession # | Gene ID: 6427, UniProt: Q01130 |
| Catalog # | orb1731387 |
| Price | $345 |
| Order / More Info | SC35 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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