APC Antibody from BIORBYT LTD.

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Antigenic SpecificityAPC
CloneFAD-1
Host SpeciesRabbit
Reactive Specieshuman, rat
IsotypeIgG
Formatunconjugated
Size100 ul, 100 ul, 100 ul, 30 ul
ConcentrationActual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
ApplicationsICC, IF, IHC, IP, WB
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DescriptionAPC Monoclonal Antibody
ImmunogenA synthesized peptide derived from human APC Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Other Namesn/a
Gene, Accession #UniProt: P25054
Catalog #orb546977
Price$520
Order / More InfoAPC Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558


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