HCV-N-G2b protein Antibody from BIORBYT LTD.

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Antigenic SpecificityHCV-N-G2b protein
Clonemonoclonal
Host SpeciesRecombinant
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size100 ug
Concentrationn/a
Applicationsn/a
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DescriptionHCV-N-G2b (residues 2-119) protein.The protein contains the HCV core nucleocapsid immunodominant regions, amino acids: 1-102. The protein isfused to a GST-tag at the N-Terminus.Hepatitis C Virus core proteins are purified by proprietarychromatographic techniques.The hepatitis C virus (HCV) core protein represents thefirst 191 amino acids of the viral precursor polyproteinand is cotranslationally inserted into the membrane of theendoplasmic reticulum (ER)Hepatitis C virus (HCV) core is a viral structural protein;it also participates in some cellular processes, includingtranscriptional regulation. However, the mechanisms ofcore-mediated transcriptional regulation remain poorlyunderstood. Hepatitis C virus (HCV) core protein isthought to contribute to HCV pathogenesis through itsinteraction with various signal transduction pathwaysIn addition, HCV core antigen is a recently developedmarker of hepatitis C infection. It is remarkably efficientat establishing persistent infection, suggesting that ithas evolved one or more strategies aimed at evadingthe host immune response. T cell responses, includinginterferon-gamma production, are severely suppressedin chronic HCV patients. The HCV core protein hasbeen previously shown to circulate in the bloodstream ofHCV-infected patients and inhibit host immunity throughan interaction with gC1qR.
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #orb97890
Price$616
Order / More InfoHCV-N-G2b protein Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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Email: info@biorbyt.com
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