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Antigenic Specificity | Transferrin Receptor / TFRC / CD71 |
Clone | TFRC/3630 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. |
Immunogen | The acute myeloid leukemia cell line KG1 was used as the immunogen for the CD71 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P02786 |
Catalog # | orb699583 |
Price | $405 |
Order / More Info | Transferrin Receptor / TFRC / CD71 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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