Retinol Binding Protein 4 / RBP4 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Retinol Binding Protein 4 / RBP4 antibody, protein, ELISA kits.
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| Antigenic Specificity | Retinol Binding Protein 4 / RBP4 |
| Clone | RBP4/4053 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2c, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity. |
| Immunogen | A portion of amino acids 29-148 from the human protein was used as the immunogen for the RBP4 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P02753 |
| Catalog # | orb699771 |
| Price | $764 |
| Order / More Info | Retinol Binding Protein 4 / RBP4 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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