Desmin (Muscle cell marker) Antibody from BIORBYT LTD.
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| Antigenic Specificity | Desmin (Muscle cell marker) |
| Clone | DES/2960R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | Protein A purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. |
| Immunogen | Recombinant human protein was used as the immunogen for the recombinant Desmin antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P17661 |
| Catalog # | orb606942 |
| Price | $764 |
| Order / More Info | Desmin (Muscle cell marker) Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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