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Antigenic Specificity | ETS1 |
Clone | ETS1/1801 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes. |
Immunogen | A recombinant human partial protein (amino acids 137-230) was used as the immunogen for the ETS1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P14921 |
Catalog # | orb639644 |
Price | $764 |
Order / More Info | ETS1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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