CD325 Antibody from BIORBYT LTD.

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Antigenic SpecificityCD325
Clone8C11
Host Speciesn/a
Reactive Specieshuman, mouse
IsotypeIgG1 kappa
Formatallophycocyanin (APC) conjugate
Size100 tests
Concentrationn/a
ApplicationsFC
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DescriptionCD325 (N-cadherin) is a type I transmembrane protein, which forms a complex with catenins, that is linked to the actin cytoskeleton. This complex is important in synapses and for functional plasticity of neurons, and is also essential for embryonic development. Decreased CD325 cleavage caused by mutations in presenilin 1 is associated with Alzheimer?s disease. Besides nervous system, CD325 is expressed on the surface of malignant T cells, and increases their adhesion to epithelia, as well as their ability to invade and metastasize to inflammatory sites.
Immunogenbacterially expressed extracellular domain of human CD325
Other NamesN-Cadherin, cadherin 2, CDHM, CDH2
Gene, Accession #Gene ID: 1000, UniProt: P19022
Catalog #orb1786029
Price$439
Order / More InfoCD325 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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St Louis, MO 63132
Email: info@biorbyt.com
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