CELA3B / Elastase 3B Antibody from BIORBYT LTD.

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Antigenic SpecificityCELA3B / Elastase 3B
CloneCELA3B/1757
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsELISA, IHC-P
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DescriptionThis mAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B), or Elastase 3B. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
ImmunogenA recombinant partial protein (aa 82-238) was used as the immunogen for the CELA3B antibody.
Other Namesn/a
Gene, Accession #UniProt: P08861
Catalog #orb750077
Price$764
Order / More InfoCELA3B / Elastase 3B Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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