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Antigenic Specificity | PDCD1 / PD-1 / PD1 |
Clone | PDCD1/7255R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | ELISA, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells. |
Immunogen | A recombinant fragment corresponding to the extracellular domain of human PDCD1 protein was used as the immunogen for the PDCD1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q15116 |
Catalog # | orb1823706 |
Price | $405 |
Order / More Info | PDCD1 / PD-1 / PD1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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