Acidic Cytokeratin (LMW / Type I) Antibody from BIORBYT LTD.
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|---|---|
| Antigenic Specificity | Acidic Cytokeratin (LMW / Type I) |
| Clone | SPM115 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 20 ug, 100 ug |
| Concentration | n/a |
| Applications | IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40kDa. MAb SPM116 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. |
| Immunogen | Solubilized keratin extract from human stratum corneum was used as the immunogen for the Acidic Cytokeratin antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q7Z794 |
| Catalog # | orb606883 |
| Price | $405 |
| Order / More Info | Acidic Cytokeratin (LMW / Type I) Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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