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Antigenic Specificity | CTSD / Cathepsin D |
Clone | CTSD/2781 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. |
Immunogen | A portion of amino acids 104-250 from the human protein was used as the immunogen for the Cathepsin D antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P07339 |
Catalog # | orb606940 |
Price | $764 |
Order / More Info | CTSD / Cathepsin D Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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