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Antigenic Specificity | CD6 |
Clone | 3F7B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IF, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular ``scavenger receptor cysteine-rich'' (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. It shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. CD6 antibody can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease. |
Immunogen | The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 923 |
Catalog # | orb749314 |
Price | $764 |
Order / More Info | CD6 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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