PDCD1 / PD-1 / PD1 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | PDCD1 / PD-1 / PD1 |
| Clone | RMP1-14 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | ELISA, FACS, IF, NeA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1 mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells). |
| Immunogen | PDCD1 transfected BHK cells were used as the immunogen for the PD1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q02242 |
| Catalog # | orb640137 |
| Price | $764 |
| Order / More Info | PDCD1 / PD-1 / PD1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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http://www.biorbyt.com
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Email: info@biorbyt.com
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