Nogo B Receptor Antibody from BIORBYT LTD.

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Antigenic SpecificityNogo B Receptor
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsWB
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DescriptionWith DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator (PubMed:16835300).
ImmunogenA synthetic peptide of human Nogo B receptor
Other NamesNgBR; MRD55; CDG1AA; C6orf68; TANGO14; MGC:7199
Gene, Accession #Gene ID: 116150, UniProt: Q96E22
Catalog #orb1731610
Price$345
Order / More InfoNogo B Receptor Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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