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Antigenic Specificity | CLEC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 100 ug, 25 ug |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CLEC1 is a C-type lectin receptor and part of the `Dectin-1 cluster' subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance. |
Immunogen | A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 51267 |
Catalog # | orb248130 |
Price | $643 |
Order / More Info | CLEC1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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