EGFR Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-EGFR antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | EGFR |
| Clone | EGFR1 |
| Host Species | n/a |
| Reactive Species | equine, human |
| Isotype | IgG2b kappa |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | FC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The oncoprotein EGFR (epidermal growth factor receptor), also known as HER1 / ErbB1, is a member of ErbB family of cell surface receptor tyrosine kinases. This 170 kDa transmembrane glycoprotein is often associated with cancerogenesis, although its activation state is controlled at various levels including trafficking and degradation steps. Binding of receptor-specific ligands to the EGFR ectodomain results in formation of homodimeric or heterodimeric kinase-active complexes into which HER2 / ErbB2 is recruited as a preferred partner. Subsequent signaling cascades such as RAS/MAPK and PI3K/AKT pathways lead to cell proliferation and survival responses. |
| Immunogen | Human epidermoid carcinoma line A431 |
| Other Names | EGF-R, Her1, ERBB1, PIG61, NISBD2 |
| Gene, Accession # | Gene ID: 1956, UniProt: P00533 |
| Catalog # | orb1821026 |
| Price | $439 |
| Order / More Info | EGFR Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240
info@biorbyt.com
http://www.biorbyt.com
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558
Profile of BIORBYT LTD.
Return to Antibodies