BRAF Antibody from BIORBYT LTD.

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Antigenic SpecificityBRAF
Clone7B10
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG2a
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsWB
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DescriptionInvolved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations.
ImmunogenPurified recombinant human B Raf protein fragments expressed in E.coli.
Other NamesBRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1
Gene, Accession #Gene ID: 673, UniProt: P15056
Catalog #orb1732641
Price$345
Order / More InfoBRAF Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
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