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Antigenic Specificity | PKC beta 1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | ICC, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. |
Immunogen | A synthetic peptide of human PKC beta 2 |
Other Names | PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta |
Gene, Accession # | Gene ID: 5579, UniProt: P05771 |
Catalog # | orb1731515 |
Price | $345 |
Order / More Info | PKC beta 1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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