KDM1A Antibody from BIORBYT LTD.

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Antigenic SpecificityKDM1A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size100 ul
Concentrationn/a
ApplicationsWB
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DescriptionRabbit polyclonal to KDM1A.Lysine-specific histone demethylase 1A (KDM1A) is a histone demethylase that demethylates both'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or acorepressor, depending on the context. KDM1A acts as a corepressor by mediating demethylation ofH3K4me, a specific tag for epigenetic transcriptional activation. KDM1A can demethylate both mono-(H3K4me1) and di-methylated (H3K4me2) H3K4me, and may play a role in the repression of neuronalgenes. KDM1A also acts as a coactivator of androgen receptor (ANDR)-dependent transcription, bybeing recruited to ANDR target genes and mediating demethylation of H3K9me, a specific tag forepigenetic transcriptional repression. KDM1A is required for gastrulation during embryogenesis.
ImmunogenN-terminal region of human KDM1A
Other NamesKDM1A,Lysinespecific histone demethylase 1A,BRAF35HDAC complex protein BHC110,Flavincontainingamine oxidase domaincontaining protein 2,AOF2,KDM1,KIAA0601,LSD1
Gene, Accession #UniProt: O60341
Catalog #orb66997
Price$527
Order / More InfoKDM1A Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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