Neurofilament (-Light) / NF-L / NEFL Antibody from BIORBYT LTD.

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Antigenic SpecificityNeurofilament (-Light) / NF-L / NEFL
CloneNR-4
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG1, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsFACS, IF, IHC-P
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DescriptionThis mAb reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.
ImmunogenCrude neurofilament preparation from porcine spinal cord was used as the immunogen for the Neurofilament antibody.
Other Namesn/a
Gene, Accession #UniProt: P07196
Catalog #orb749717
Price$764
Order / More InfoNeurofilament (-Light) / NF-L / NEFL Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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